Dental Fluorosis: Dilemma of Genetic Susceptibility | Asian Journal of Dental Sciences

Excessive exposure to fluoride during formation of teeth may lead to a severe hypomineralization condition, called dental fluorosis. Genes such as Collagen type 1 alpha 2 (COL1A2), Estrogen receptor (ESR), Prolactin (PRL), Catechol-o-methyltransferase (COMT), matrix metalloproteinase 20 (MMP20) and many others have been implicated in the incidence of dental fluorosis. This mini-review is an insight into the fact that fluorosis incidence and intensity are significantly related to individual’s genetic background. Please read full article - http://www.journalajds.com/index.php/AJDS [if !supportLineBreakNewLine] [endif]