An Unusual Presentation of Primary Skin Amyloidosis | Asian Journal of Research in Surgery
Amyloidosis is a group of diseases in which abnormal proteins, known as amyloid fibrils, build up in tissue. Primary localized cutaneous amyloidosis is a form limited to the skin without involving any other localization. An amorphous material composed of amyloid is produced and deposited in the dermis, with a varied clinical presentation. Nodular amyloidosis is a rare presentation of primary localized skin amyloidosis. We report an unusual clinical presentation made of bilateral nodular lesions, mimicking a skin tumor. Anatomopathological study showed primary localized nodular skin amyloidosis. Surgical excision with reconstruction was performed in view of the unsightly appearance of the lesions. Regular monitoring is necessary to detect any potential systemic progression of the disease. The patient uneventfully recovered without recurrence at the one-year follow-up.
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