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An Efficacy of Treatment Methodologies of Bovine Cutaneous Papillomatosis Using Combined Therapy: A

Introduction: Bovine papillomatosis (BP) is a contagious proliferative illness of cattle that is characterised by warts or papilloma that appear predominantly on the skin but also on the mucosa as exophytic papilloma.

The goal of this study was to determine how a combination therapeutic approach for treating bovine cutaneous Papillomatosis in animals worked.


A case of bovine papillomatosis in a cow is reported, along with its treatment with an autogenous vaccination, auto-hemotherapy, homoeopathic, and allopathic drugs. A four to five-year-old female Holstein Friesian crossbred cow was diagnosed with cauliflower growth of various diameters and pedunculated cutaneous warts on the neck, shoulder, and teat, as well as pain, bleeding, and milking interference. It was diagnosed as bovine papillomatosis based on the history and clinical symptoms. The vaccine was prepared from sample collected from older wart growths under aseptic conditions, minced, suspended in normal saline, filtered through muslin cloth and treated with formalin. The animal was treated with a dose of 5 ml subcutaneously and revaccinated at 7 day intervals for four weeks. The animal was also treated with its own blood and repeated once in a week. The animal was treated with homeopathic medicine Thuja-mother tincture and Thuja 200X and allopathic medicine Levamisol at dose of 2.5 mg/kg/day on days 1,3,5,7,9 and 16 by per oral route, single shot of Ivermectin (S/C) @ 200µg/kg body wt .The animal was recovered completely in six weeks.


Discussion and Conclusions: Because a single treatment technique is ineffective, recovery is poor, and recurrence is a possibility. Based on the findings of our research, combination therapy is recommended for the treatment of Bovine cutaneous Papillomatosis.


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