Comparison of Anti-Tuberculosis Treatment Outcomes of Pulmonary Tuberculosis in Current, Ex and...
The aim of this study was to look for treatment results in newly diagnosed pulmonary tuberculosis patients who were current smokers, ex-smokers, or nonsmokers. Methodology: This cohort prospective research was carried out in the department of Microbiology, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre Karachi, with the aid of various (DOTS) pathology centres at Karachi Medical and Dental College. All newly diagnosed pulmonary tuberculosis patients, regardless of gender, who had registered for care were included. Three groups of patients were formed. Current smokers are in Group A, ex-smokers are in Group B, and non-smokers are in Group C. The patients were followed for a period of six months. The outcome was determined by whether the patient was healed or not. All of the data was entered into a pre-designed proforma. SPSS version 20 was used to analyse the data. Nonsmokers' average age was 44.2017.73 years, ex-smokers' average age was 43.1315.67 years, and smokers' average age was 38.0715.67 years in this report. Males dominated all study categories, with ex-smokers accounting for 98.75 percent, non-smokers accounting for 90.0 percent, and smokers accounting for 92.50 percent. At the start of therapy, smokers weighed 55.505.41 kg, ex-smokers weighed 48.919.00 kg, and non-smokers weighed 48.717.04 kg. P = 0.001 Nonsmokers had an ESR of 89.3110.02, ex-smokers had an ESR of 82.6212.18, and smokers had an ESR of 80.6115.83 when they started therapy. P = 0.001 After 6 months of therapy, nonsmokers had a cure rate of 96.25 percent, smokers had a cure rate of 90 percent, and ex–smokers had a cure rate of 93.75 percent. Conclusion: Nonsmokers had a high cure rate, according to this report. Individuals' smoking status has a significant impact on tuberculosis care outcomes, with a higher failure rate.
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