Hypo-magnesium and Hyperlipidemia Responsible for Hypertensive Status of Pregnant Women in ...

Background/Objective: Pregnancy-induced hypertension (PIH) is a major cause of maternal death around the world. It can be the cause of complications such as hemodilution, impaired lipid metabolism, and mineral deficiencies in the body. Despite the fact that the causes of pregnancy-induced hypertension (PIH) are unknown. The aim of this research was to see how magnesium serum levels and lipid profiles changed in hypertensive and normotensive pregnant women. Materials and Methods: A 60-person sample was used in an analytical case control analysis. 30 pregnant women with normal blood pressure served as the control group (A) and 30 pregnant women with pregnancy-induced hypertension served as the case group (B) (B). Patients with pre-existing hypertension were not allowed to participate.The analysis of different parameters between groups A and B was done using the independent t-test. In comparison to the normotensive population, PIH (B) had significantly higher levels of triacylglycerol (TAG) and low density lipoprotein cholesterol (LDL-C) (A). In the PIH and normotensive classes, mean serum TG values were (195.73 70.28 vs 156.27 55.60 mg dL-1) and LDL-C vs control (87.33 37.74 vs 69.45 28.58 mg dL-1) respectively. HDL-C was measured in PIH vs Control (47.401.12 vs 54.431.27 mg dL-1) and Mg+2 was measured in PIH vs Control (1.360.07 vs 1.940.35 mg dL-1). In PIH, the levels of high density lipoprotein cholesterol (HDL-C) and magnesium Mg+2 were significantly lower. Conclusion: Lower serum magnesium levels and an irregular lipid profile in pregnant women may indicate a role as risk factors for the development of PIH. As a result, early detection of hypomagnesemia in PIH patients may aid in the reduction of complications and the creation of new cure strategies.

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