Malarial Related Myopathies: A Rhabdomyolysis Story | International Journal of Pathogen Research

Malaria is one of the most common and epidemiologically significant parasitic protozoaninfections on the planet. Millions of people are infected each year, mostly in Southeast Asia and Sub-Saharan Africa.

Its morbidity and mortality are still uncontrollable, and eradication is still a long way off.

Children and pregnant women are among the population's most endangered.

Its pathobiology has been linked to rhabdomyolysis, a condition in which the patient's skeletal muscle is damaged directly or indirectly. Even though it is very uncommon, it has the potential to be fatal and deadly.Very strong inflammatory response, widespread red cell sequestration in muscle capillaries due to extreme anaemia, and parasite toxins are three mechanisms of malariarelated rhabdomyolysis that may contribute to or increase the risk of complications. One of the first signs of extreme malaria is the derangement of particular types of muscle such as skeletal and cardiac. In the future, more research is needed, particularly on important topics such as mechanism and impact, signalling pathways, laboratory best practises, and management strategy best practises.

Please see the link - https://www.journalijpr.com/index.php/IJPR/article/view/30137