Multiple Viral Co-infections in a Pediatric Patient of Acute Encephalitis Syndrome (AES) - An Unique

The occurrence of viral co-infection is usually a difficult issue in paediatrics, indicating that the responsible viral pathogens are underestimated. In February 2020, a 6-year-old girl from Patna was identified with an uncommon instance of multi-viral co-infection. She had unconsciousness, as well as a high-grade temperature, weakness, a nasal bleed, a headache, and a body discomfort. Her sensorium was disturbed, and her pupils were somewhat dilated. Kernig's sign, Brudzinski's sign, and nuchal stiffness, three typical meningeal signs, were all positive. With a high suspicion of viral infectivity, she conducted a clinical investigation. Unfortunately, she was diagnosed with a multi-viral co-infection that included Japanese encephalitis, Dengue fever, Chikungunya, Cytomegalovirus, and Rubella, with HSV and VZV identified on the borderline. The IgM detection of JE in a CSF sample was found to be ambiguous. CECT brain scanning also verified the illness. Antiemetic, antipyretic, antiepileptic medications, antibiotics, antiviral treatments, and 20 percent Mannitol were given to her to help with the intracranial pressure. She completely recovered from any seizures and viral infections after taking medication under careful physician monitoring. She suggested that we meet again in a month. Multi-viral co-infections of this nature require special attention and education among healthcare professionals on the dangers of drugs.

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