Sero-conversion after Second Measles' Containing Vaccine in a Selected Sample of Young Children | Jo

Background: This research aims to detect sero-prevalence of measles Immunoglobulin-G, antibodies, (IgG Abs) before versus after second measles containing vaccine (MCV2) in young children.

Methodology: This cross–sectional research was performed in a selected primary health care centers (PHCcs), in Iraq. The research sample included 112 children (66 males & 46 females) aged 13 - < 24 months, randomly selected for routine vaccination during their attendance. The research sample was submitted for measles IgG Abs titer estimate before and (4-12) weeks after vaccination with Measles, Mumps & Rubella (MMR).

Results: Seroprevalence of particular measles IgG-Abs before MMR vaccine (41.8%) was observed among those infants when the seroconversion rate was measured after MMR vaccination (92 .4 percent ). The result indicates that the seroconversion rate was (96.8 percent) for children who had previously received the MCV1 vaccine, while 84.0 percent had not previously received the MCV1 vaccine for those children.

Conclusions: This study concluded that the two-dose regimen tends to improve the seropositivity rate and proposed that two doses of safe and effective measles vaccine be included in a solid vaccination program prior to the second year of age.

Please see the link :- https://journaljpri.com/index.php/JPRI/article/view/30851