Spectral-Domain Optical Coherence Tomography and Multifocal Electroretinography Results in the Long-
The goal of this study was to look at how changes in macular retinal layers and panretinal neuroretinal functions changed over time in patients with primary open-angle glaucoma.
Materials and Methods: A total of 41 individuals with primary open-angle glaucoma were observed for a year. The patients were divided into two groups based on their mean deviation (MD) values: Group 1 had early stage glaucoma (MD-6) and Group 2 had middle-advanced stage glaucoma (MD-6). At the baseline, the sixth and twelve-month evaluations, optical coherence tomography (OCT) and multifocal electroretinography (mfERG) were performed. The findings of the OCT, retinal layer, and mfERG were compared in the two groups.
In terms of gender and age, there was no statistically significant difference between the groups. In comparison to Group 1, Group 2 had decreased mean baseline macula Retina Nerve Fiber Layer, Ganglion Cell Layer, and Inner Pleksiform Layer measures in each quadrant. There was no significant difference between the two groups in terms of OCT measures advancement. However, there was a decrease in the first and second ring amplitudes of the P1 and N2 waves, as well as a prolonging of the implicit time, in Group 2. In Group 1, there was a decrease in the P1 wave amplitude and a prolonging of the implicit duration of the N1 wave at the 12-month evaluation.
In patients with intermediate and severe glaucoma, the retinal layers are damaged. mfERG readings can be used to detect damage in patients with early-stage glaucoma.
Please see the link :- https://www.journalor.com/index.php/OR/article/view/30175
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