Status Dystonicus in Children with Secondary Dystonia: Reporting 3 Cases of Cerebral Palsy, Leigh ..

Status dystonicus (SD) or dystonic storm occurs in patients with primary and secondary dystonic syndromes. This is a terrifying hyperkinetic movement condition that necessitates immediate medical attention. A marked, rapid exacerbation of dystonia necessitates immediate medical attention and hospital admission. It's crucial to spot dystonic storm early on to distinguish it from other hyperkinetic movement disorders because it can cause metabolic problems like rhabdomyolysis, which can lead to acute renal failure. The aim of this paper is to present three SD cases. To illustrate the mode of presentation, diagnosis, treatment, and outcome of secondary dystonia with various etiologies, all of the patients had secondary dystonia with different etiologies. Methodology: We present three cases of serious secondary dystonia that progressed to SD and required hospitalisation. Both three patients were treated and admitted to a tertiary care hospital. One patient was admitted to the intensive care unit. In a nutshell, the first case involved a 5-year-old boy with dyskinetic CP who was treated with infusions of trihexiphenidyl (THP), baclofen, and midazolam. The second case involved a 15-month-old boy who had been diagnosed with mitochondrial encephalopathy (Leigh disease) and was treated with THP, baclofen, haloperidol, clonazepam, and midazolam infusion. The third case involved a 13-month-old boy who had been diagnosed with a Molybdenum Cofactor deficiency and was given THP treatment. They declined to take tizanidine, but they did take midazolam. Conclusion: Three cases of SD with different etiologies were identified in this case series, along with clinical characteristics, treatment modalities, and outcomes.

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